Publications
2020
One of the most promising methods for non-covalent inactivation of vaccine-producing microorganisms is the use of photoinactivation using riboflavin derivatives.
2019
Multi-drug resistant strains have arisen over the years due to over use of antibiotics in hospitals and in the veterinary space.
In one patents demonstrated the riboflavin ability to inactivate vaccine strains of viruses and bacteria, as well as cancer cells during the production of vaccines.
2018
The article provides an overview of the current state of the use of TRIZ in the pharmaceutical industry and our R&D efforts in that area
The anticancer activity of antisense microRNA (fRNA) in combination with the lectin from Bacillus subtilis B-7025
Many adenocarcinomas have the ability to capture from an extracellular matrix the oligonucleotides and nanoparticles by pinocytosis, when the non-cancerous cells are not capable to capture the oligonucleotides and small liposomes.
2017
The control over multi-resistant nosocomial strains of microorganisms has been becoming increasingly urgent in recent years.
2016
Quercetin is a flavone derivatives which known like a substances with vitamin activity, high antioxidant, antimutagenic and anticarcinogenic activity and many other types of biological activity.
As a result of years’ research of the many research groups around the world able to understand the reason why it will be impossible to create really effective vaccine for the prevention of tuberculosis infection in the near future.
Introduction. The key element in the formation of tuberculosis infection (TI) is the inability of alveolar macrophage to complete phagocytosis of mycobacteria absorbed by them, that caused by both features of the pathogens biology and the tissue macrophages.
This brief review concerns the basic principles of structural organization of multi-subunit bacterial ureases and formation of their quaternary structure.
2011
Research has been conducted on the chemical and biological properties of combinatorial succinylated derivatives of interferon-γ with various levels of acylation, which create quasi-life, self-organizing ensembles.
Introduction: Since 1997, we have beenstudying the role of herpes viruses in thedevelopment of cancer and trying to deter-mine the reason tumors are invisible to theimmune system.
2007
The crystal complex of β-cyclodextrin with succinic acid, intermediate product of hydrolysis reaction of succinic anhydride in the presence of β-cyclodextrin, was isolated and studied by X-ray analysis
2005
The antiproliferative activity of aconitylated (AIFN) and succinylated (SIFN) derivatives of recombinant interferon- alpha2b (IFN-alpha2b) was examined.